Biotechnology Research in Bulgaria

Nasekomo

Who we are: A collective of entrepreneurs, scientists, and experts dedicated to a sustainable future. What we do: We rear Black Soldier Fly to produce protein, oil, and fertilizer for the feed and agriculture industries. Where we do it: We chose Bulgaria as home to our first industrial-scale production facility; it’s close to vital markets such as Greece, Turkey and Western Europe, as well as offering advantageous labor and business conditions.

51 to 200 staff

Ridacom Ltd

We believe science is the main driving force behind human progress. We strive to help researches bring new developments and innovations that positively impact our healthcare and environment. We are committed to making science as exciting and intriguing as we see it. Powered by the expertise of our people RIDACOM delivers personalized products solutions to the fields of life science, microbiome analysis, genomics and precision medicine, pharma and biotechnology.

11 to 50 staff

Amgenlab

Reseller of DNA relationship testing services: paternity, maternity, siblingship testings, immigration, forensic and infidelity. Works with major American DNA laboratories such as DDC (Ohio), IntelliGenetics (S. Corolina) and DNA Match (S.C.) Also offers DNA test for animals.

1 to 10 staff

Biokom Trendafilov Ltd

Биоком Трендафилов" ЕООД е утвърден лидер в предлагането на съвременни и иновативни решения за безопасност и хигиена на суровини, крайни продукти и повърхности в цялата хранителна промишленост, търговски вериги, хотели, ресторанти, заведения за хранене, кетъринг фирми, лечебни заведения; лаборатории, козметика, фармация, зърнопроизводители, зърнопреработватели, фермери, ветеринарни обекти. Нашата принципна позиция, от която се ръководим в дейността си е опазването на здравето на човека чрез безопасно производство и разпространение на качествени храни по цялата хранителна верига -"от полето до вилицата". Фирмата е изключителен представител на утвърдени световни производители на модерни научни технологии за микробиологичен и физикохимичен мониторинг на храните. Освен това, съвместно с водещи учени и специалисти в съответния бранш разработваме собствени иновативни продукти, съобразени с нуждите на нашите клиенти.

51 to 200 staff

Enthela

Mineral fertilizers are expensive in a volatile market.+50% of the mineral fertilizers don't get absrobed by plants which makes them cost-ineffective and they also pollute the environment. Producing those fertilisers also pumps out about 1 % of global CO₂. Our solution Enthela replaces part of the mineral fertilizer (NP) with a bio-based fertiliser made from naturally occurring, nitrogen-fixing bacteria. Our micro-encapsulation keeps the microbes alive 5× longer and delivers +42 % nitrogen compared with uncoated strains. On-farm impact • Save up to 30 kg synthetic N per hectare and up to 20kg Phosphorus • 30 % yield lift in early vegetable trials • Zero nitrate run-off and lower greenhouse-gas emissions Where we are now • Lab proof-of-concept achieved (Nov ’24) • Field trials under way with Sofia University & Early adopters • Commercial scale in March 2026 🤝 Get involved We’re enrolling progressive growers and distributors for the 2026 pilot season across Central & Eastern Europe and Southern Europe.

1 to 10 staff

Micar Innovation Micar21.Com

Micar Innovation is a drug discovery factory. The company has found a niche where it is able to create a large societal impact by improving the quality of life through new blockbuster drug molecules for a large class of diseases. Micar Innovation focuses on non-clinical Proof-of-Concepts (POCs) in preclinical R&D and Hit-to-Lead (H2L) achievements in areas such as neuroscience, oncology, cardio-vascularity, dermatology, rare diseases. Micar21 is our drug discovery platform for small molecule drug candidates. The business model is based on licensing our intellectual property to commercial partners and on the creation new spin out companies. MICAR INNOVATION (MICAR21) IS THE WINNER OF А PRESTIGIOUS AWARD FOR INNOVATIVE STARTUP ENTERPRISE OF THE YEAR 2018 Тhe 14th edition of the competition “Innovative Enterprise of the Year – 2018” took place during the National Innovation Forum on 6 December 2018. The Forum with the participation of the President of the Republic of Bulgaria Mr. Rumen Radev features the award ceremony of the Innovative Enterprise of the Year 2018 national contest. For Innovative New Startup Enterprise, Micar Innovation (Micar21) was awarded an honorary certificate. Micar Innovation (Micar21.com) received the CIDIC/European Diplomatic, Economic & Academic Centre/ award for its well-chosen positioning in a complex and long value chain, where it can create key-value contributions by delivering no-clinical PoCs. The company can be described as a fountain of intellectual property and an IP broker for new pharma startups and the big pharma industry. Micar Innovation is winner of the Best Biotech Startup 2017 award by the 4th CEE Startup Awards. The good news is that the world renowned market analysis agency Roots Analysis published a study on the main players in “Computer-Aided Drug Discovery Services Market 2018-2030”. Our company, Micar Innovation, is one of the world’s 250 companies in the report alongside corporations such as Sanofi, Merck, etc.

1 to 10 staff

Industrial Plants Ltd

Industrial Plants Ltd: Pioneering Plant Tissue Culture Since 2008 Established in 2008, Industrial Plants Ltd. was Bulgaria's first private commercial plant tissue culture laboratory. We specialize in the micropropagation of high-quality, virus-free young plants, supplying them to European nurseries, producers, and international markets. Being situated in an EU country simplifies logistics and sales throughout the European market. Our expertise lies in producing superior in vitro young plants, ensuring genetic purity and health for optimal crop success. We offer flexibility in delivery - plants ex-vitro, directly from our lab or finished young plants acclimatized in substrate trays or pots from our modern acclimatization facilities and greenhouses. Our Services & Products Include- Fruit Tree Rootstocks - Soft Fruits, including elite strawberry stock and young plants - Medicinal and Aromatic Plants, including protocols for difficult-to-propagate species - Contract propagation of specific plant varieties based on customer requests. We are actively seeking partnerships with: Commercial strawberry growers looking for premium, disease-free elite strawberry stock. Ornamental and horticulture growers needing high-quality ex vitro plants for their operations. Our experienced R&D team continuously develops new technologies and protocols, expanding our plant variety list. Visit our website for more information on the plant varieties we micropropagate:

11 to 50 staff

Vodoraslo

Algaia’s project VODORASLO is developing a domestic photobioreactor device for air purification using algae as the main resource. The product is an indoor air solution for homes, schools, and offices where it can purify gases like CO2, NOX, SO2, and bigger pollutants such as PM2.5, PM10, and VOCs. It is working based on photosynthesis where algae are “eating” the gases to produce oxygen and biomass. The biomass can be used as a natural fertilizer for plants, biodegradable packaging, food supply, pigment or in cosmetics. VODORASLO already developed its first device in 2021, created one hundred MVPs, and donated them to 25 Bulgarian schools. The company is working on a second prototype right now. A long-term target is to develop more complex B2B installations for bus stops, schools, hospitals, kindergartens, public space and buildings. VODORASLO is working also on long term project in the field of material science and development of algae and seaweed based products like plastics.

1 to 10 staff

Innova Bm

We are Innova BM. We help cosmetic companies obtain a competitive edge by providing them with natural, highly efficient and innovative active ingredients that make a real difference for the consumer. We constantly innovate by applying the most advanced biotech methods and pushing the boundaries of science further. Our plant stem cell and in vitro cultures form the basis for highly potent and multifunctional active ingredients. We are proud that we contribute to a more sustainable and eco-friendly world. Our R&D and production processes help protect the environment, preserve biodiversity, prevent soil depletion and reduce the carbon footprint.

11 to 50 staff

Os Education

OS Implants is a biotech company which develops and creates clinical and educational 3D printed products, helping humanitarian and veterinary doctors with complex medical cases that need personal approach. Our surgical models represent a patient's bone trauma in a 3D prospective using a patient’s computer tomography scan and are used for pre-surgical planning. Our surgical guides are 3D printed single-use patient-specific medical devices that help to prevent inaccuracies during surgery and to make the pre-surgical plan a reality. Our educational anatomical models help students achieve a better study efficiency and become successful professionals. In the beginning of 2021 we start developing VR for our models, which makes us one of the few companies in the world to do so.

11 to 50 staff

Prolact Probiotics

ProLact probiotics is based on over 30 years of experience in the study and science in the field of probiotics and space food. We are dedicated to the production and distribution of all natural probiotics. ProLact offers all natural probiotics, based on highly concentrated form of yoghurt with Lactobacillus Bulgaricus and a blend of carefully selected "good" bacteria. ProLact probiotics are based on the initial development of space food for the international space program Intercosmos. ProLact's unique microencapsulation technology, preserves the live strains for a very long periods of time at room temperatures. ProLact's optimised low production costs and the use of standard industry equipment, allows us to be the most competitive probiotic company on the market. ProLact offers various business opportunities, including: retail product export, bulk purchase, private label probiotics, multi-level marketing franchise, as well as manufacturing technology licensing.

11 to 50 staff

Daflorn Ltd

Laktera all natural probiotics with Lactobacillus bulgaricus DWT1 - the first probiotic in the world of water origin. Laktera is patented in USA and EU and certified for FSSC 22 GMP, Kosher and Halal.

11 to 50 staff

Global Medical Solutions Gms

Global Medical Solutions is a company specialized in providing branch-specific outsourcing services to Pharma, Biotech and CRO companies, conducting clinical trials. Our main areas of business include- rental, leasing and selling of medical equipment - performing payments to sites, investigators, patients on behalf of Sponsor/CRO - EU Legal Representation-services - Specialized full legal support If you are experiencing difficulties performing specific activities or want to find a cheaper alternative, we would gladly offer your business an outsourcing solution- Why to choose our Rental and Payment solutions- Cost and time saving - No accounting issues - Increased CRO’s efficacy - Full compliance with anti-corruption legislation & voidance of any corruption suspicions - Full transparency - Flexibility - Our services being used by some of the biggest CROs and Biotech companies - Why to entrust GMS with your EU-Legal Representation- Located in an EU-member state with EU-legislation - Really low local taxes – only 10 % general profit tax - Synchronized clinical trials regulations and procedures - Convenient EET- time zone (London + 2 hours) – overlapping with US, UK, EU and Asia- Experienced team - Low costs

11 to 50 staff

Organic Invest Bio Protection Ltd

Organic Invest Bio Protection Ltd is a leading Bulgarian company dedicated to sustainable agriculture through innovative biological pest control. Our mission is to reduce chemical pesticide use by offering effective, eco-friendly solutions like Trichogramma — tiny parasitic wasps that protect crops naturally. From our high-tech production base in Doyrentsi, we provide farmers with efficient, affordable, and environmentally responsible pest management tools. Whether you’re cultivating cereals, corn, or fruits, our biocontrol solutions are tailored to your needs. Backed by scientific expertise and practical results, we’re committed to helping farms grow healthier food — for people, pollinators, and the planet. Visit trichogramma.bg or message us to learn how we can help your crops thrive.

11 to 50 staff

Alphyca

1 to 10 staff

Entireworld Ltd

1 to 10 staff

Bcrs Scientific Inc

BCRS is a full-service Scientific Research Organization (SRO), an experienced and innovative provider of human biological materials for research. We are a privately held company, founded in 2012. Our subsidiaries in Belgrade SER; Budapest HU, Prague CZ, Ljubljana HR, and Skopje MK are supporting our efforts to reach as big as possible diversity of indications and samples.

11 to 50 staff

Biotech Atelier

Biotech Atelier - The European annual biotech conference uniting all stakeholders across Biotech, Healthcare, IT, Life Sciences, and Pharma. In 2021 Biotech Atelier presents a Special Edition on "Water and Biotechnologies", which is dedicated to facilitate a dialogue between utility companies, start-ups and larger business entities in the area of biotechnological developments and their application in the water sector. We would like to outline the specific bridges between water and the application of biotechnological tools and innovations. Mission Biotech Atelier brings all relevant stakeholders together to promote innovation, idea sharing, and interdisciplinary exchange on an international scale. Our mission is to build international bridges, drive commercialization and ultimately spark the next substantial leaps across Europe. Story Biotech Atelier started in 2018 as a joint initiative of Prescriptia (Pharma Consultancy), the Bulgarian Association of Personalized Medicine – BAPAMED. Since the first event a few years ago, every next year we have been increasing the number of international speakers and guests, whereby for Biotech Atelier 2020 we’ve reached 70+ speakers and up to 500+ participants. Futurists. Business leaders. Investors. Think tanks. Scientists. Entrepreneurs. And you!

11 to 50 staff

Printivo

Printivo is startup company operating in the field of Biotechnology. Currently we are situated in Sofia, Bulgaria. Our motto – “We print life” is the quintessence of our main goal namely to fabricate and design native-like human tissues and organs. Our inspiration is driven by the huge necessity of finding solutions for the growing humanitarian problem with shortage of organ transplants. Hundreds of people die each day, in this very minute in fact, failing to receive organ transplantation. This life-giving act must be accessible and affordable to each person and we are ready to take this difficult, uncertain and long way to fulfill their needs.

1 to 10 staff

Gennome

Project Gennome uses an innovative approach applied for the first time in the Preclinical Phase of the Drug Discovery to find a comprehensive personalized medicine treatment for breast cancer. We call it the “Full Coverage Solution”, where: • We target all known genetic mutations associated with a disease (in this case - 110 mutations associated with breast cancer) and • We are looking for a new personalized treatment for each mutation. We do that by using our improved structure based in silico Drug Discovery Platform that allows the effective detection of new drug candidates - small molecules (with a molecular weight below 900 daltons) with distinct pharmacological properties. Our unique advantage is that: • We cover all stages up to IND, providing accurate predictions (with over 70% accuracy) about the ADMET activity of potential drug candidates. • Significantly improved speed of discovery. Depending on the complexity, we can develop potential drug candidate in 2 to 8 weeks, including predictions of its further activity (up to synthesis of the compounds and start of biological testing). By comparison, with most in silico technologies, this step takes from 6 to 18 months. Shorter R&D duration results in cost reductions and improved financial performance such as time to market (TTM).

1 to 10 staff

Scientific Biotech Bulgaria

Медицинско изделие за създаване на напълно автоложен серум чрез центрофугиране. Използването на нашето специално разработено медицинско изделие създава автоложен серум, богат на цитокини, който може да бъде извлечен от кръвта на пациент. Не е необходимо използването на изкуствени добавки. Специално проектираните стъклени сфери могат да задействат напълно естествен процес в кръвта на пациента, за да създадат изключително полезен и 100% автоложен серум. Предлагаме индивидуални комплекти с всички необходими продукти за извършване на терапията. Продължаваме с научните изследвания, за да можем да подобрим нашето медицинско изделие и през следващите години да го направим още по-ефективно. Тепърва започваме да развиваме възможностите на биотехнологиите.

1 to 10 staff

Sanakin Bioscience

Inflammation is the main cause of many degenerative diseases and has a major impact on regeneration after injury and surgery. The result of persistent inflammation is always progressive tissue damage and further deterioration. For this reason, physicians are constantly striving to regulate inflammation quickly and reliably. Autologous serum therapies offer the latest, most effective and safest approach to achieving this in a completely natural way. Sanakin BioScience specialises in the development and distribution of equipment that enables the production of a fully autologous serum containing high levels of anti-inflammatory and regenerative cytokines. This Autologous Cytokine Rich Serum (ACRS) can be used in various medical specialities. Does this sound interesting to you? For doctors: For vets:

1 to 10 staff

Sogrow Llc

SoGrow is an innovative company in the field of production and trade in liquid fertilizers, bio stimulants and soil improvers for plants. The products offered are based on biological raw materials of good quality, integrated in each stage of plant development. All SoGrow products are developed on the basis of innovations and product technologies as a result of accumulated experience and research. These products are needed for the vital functions of plants and soil care. During the years of development since 2007, the constantly changing climatic factors and the requirements for more durable plants and a better harvest have been the main motivator for the company Soil care has always been the most important factor in these requirements. This care for the soil is inherent to the farmers who buy SoGrow products. Our purpose is to develop our product portfolio in accordance with changing climatic factors, increasing requirements for a healthy and good quality harvest as well as soil protection.

1 to 10 staff

Vibrate Lab

VIBraTE Lab is an innovative research center established as part of the VIBraTE project, funded by the European Commission. The lab is dedicated to studying the mechanics of brain-computer interfaces (BCIs) and their interaction with neural tissue. Based at the Institute of Information and Communication Technologies (IICT) at the Bulgarian Academy of Sciences, it brings together experts in neuroscience, biomedical engineering, and computational modeling to foster innovation in neurotechnology and enhance the safety and effectiveness of BCI systems.

11 to 50 staff

Fsb Products

FSB Products (Friendly Science Bioproducts) is an innovative biotechnology company focused on developing and offering high-quality, eco-friendly products designed for innovative and sustainable agriculture. The company strives to combine the latest scientific discoveries with the practical needs of farmers, providing solutions that stimulate crop growth, protect the environment, and improve yields.

1 to 10 staff

Liaisonex Medical Group

founded by Healthcare Professionals, dedicated to advancing medical science and fostering collaboration between key healthcare stakeholders through highly specialised outsourced services.

1 to 10 staff

Trycatch Genomics

Provide high-end scientific and technical support in the field of Bioinformatics. Prepare training and consultations for organisations and individuals working with NGS analysis.

1 to 10 staff

Bi̇ocompost Bg Ltd

Biocompost BG LTD şirketimiz ABD'de Mikrobiyal gübre üretimi ve Biocompost üretim tesisleri kuran şirketlerimizin AB,Güney Avrupa ve Ortadoğu temsilcisidir.BIO ONE ticari markalı Mikrobiyal Gübremiz hızlı bir şekilde pazardaki payını her geçen gün arttırmaktadır. Biocompost üretim tesislerimizin yer aldığı projeler üzerinde çalışmalarımız devam etmektedir!

1 to 10 staff

Пептиди

От древни времена, учените са се опитвали да разберат от какво тялото застарява. В природата на човек е заложена продължителност на живота 110-120 години. Стареенето започва постепенно, първо започва забавяне биохимичните реакции, намалява функцията на мозъка, сърцето, черния дроб и т.н. И едва когато се появят симптоми, т.е. появата на бръчки, прошарена коса, ставни проблеми, това са вече последствия. Живота съществува благодарение на две молекули: ДНК, която е матрицата и сама по себе си не е активна и молекули на пептиди, които активират желаните целевите региони на ДНК. При свързване на пептиди с определена ДНК последователност, т.е. с част от гена, настъпва синтеза на специфични протеини, възниква живот.

1 to 10 staff